Email: yanghaoxiang7@gmail.com

About me

I am a first-year neuroscience PhD rotation student at Johns Hopkins University. I received my Bachelor’s degree in Computer Science from Turing Class, Peking University and Master’s degree in Electrical and Computer Engineering at Carnegie Mellon University.

My interest lies in understanding the key regulators of aging to develop targeted therapeutics with leading technologies. I did research on lysosomal quality control and molecular mechanism in aging and aging-related diseases at Aging Institute, University of Pittsburgh School of Medicine (UPMC) with Dr. Jay Tan as mentor and closely work with Dr. Toren Finkel. See my Resume for a full list of experience.

Research Interest

I focus on cellular and molecular mechanisms of aging, such as how to activate or reprogram existing mechanisms to slow down aging, how to utilize omics and computations to identify key regulators, and how to develop potential therapeutics for aging and aging-related diseases.

Publications

See Google Scholar for a latest list of papers.

Lysosomal quality control: molecular mechanisms and therapeutic implications. Haoxiang Yang, Jay Xiaojun Tan. Trends in Cell Biology, 2023.

A TBK1-independent primordial function of STING in lysosomal biogenesis. Bo Lv, William A Dion, Haoxiang Yang, Jinrui Xun, Do-Hyung Kim, Bokai Zhu, Jay Xiaojun Tan. Molecular Cell, 2024.

A conserved ion channel function of STING mediates non-canonical autophagy and cell death. Jinrui Xun*, Zhichao Zhang*, Bo Lyu*, Defen Lu*, Haoxiang Yang, Guijun Shang, Jay Xiaojun Tan. EMBO Reports, 2024.

The PITT pathway: Keeping lysosomes young. Haoxiang Yang, Jay Xiaojun Tan. Clinical and Translational Medicine, 2022.

Resume

Link

Previous experience and coworkers

During M.S. at Carnegie Mellon University

UPitt, 2022-2024 Advisor/Mentor: Dr. Jay Xiaojun Tan; also working with Dr. Toren Finkel

During B.S. at Peking University

PKU, 2021-2022 Advisor: Dr. Yizhou Wang: Mentor: Fangwei Zhong; Co-worker: Kejuan Yang

Stanford, 2021 Advisor: Dr. Leonidas Guibas; Mentor: Yanchao Yang, Kaichun Mo

Mila, 2021 Advisor: Dr. Jian Tang; Mentor: Chence Shi, Huiyu Cai; Co-worker: Chang Ma

Last updated: Jan 29, 2025